Oral Glucose-Lowering Agents vs Insulin for Gestational Diabetes: A Randomized Clinical Trial.

Importance: Metformin and glyburide monotherapy are used as alternatives to insulin in managing gestational diabetes. Whether a sequential strategy of these oral agents results in noninferior perinatal outcomes compared with insulin alone is unknown.

Objective: To test whether a treatment strategy of oral glucose-lowering agents is noninferior to insulin for prevention of large-for-gestational-age infants.

Residential Mobility in Childhood and Union Dissolution Later in Life.

The limited existing literature studying the effects of childhood residential mobility suggests that it influences a range of life outcomes, at least in young adulthood. Little is known about how the frequency of moving in childhood is related to later-life demographic behaviour in Europe. Drawing on residential and partnership histories from the Survey of Health, Ageing and Retirement in Europe (SHARE), this paper examines whether moving in childhood relates to union dissolution in adulthood.

[Appropriate periodontal care: a historical case in light of minimally invasive care].

A 39-year-old woman with severe periodontal inflammation was referred to a periodontist in 2013. Intraoral examination and additional diagnostics revealed generalized periodontitis, stage IV, grade C, with the presence of Aggregatibacter actinomycetemcomitans in the subgingival plaque, according to current classification. Treatment and treatment outcomes are described, followed by consideration of the treatment decisions in light of minimally invasive care and current treatment guidelines.

Mortality patterns in Dutch diabetes outpatients.

Aim: Diabetes mellitus is a major cause of death. Outpatients with diabetes have more complications than patients in general practice; mortality patterns have only been studied in the total diabetes population. This study aims to assess mortality, causes, and predictors in outpatients with diabetes.