Publications by authors named "H M Higgins"
Introduction: Neonatal infectious arthritis (NIA) is a bacterial disease of lambs in the first month of life. NIA is associated with poor animal welfare, economic losses, and prophylactic antibiotic use. Farmers report problems with NIA despite following current guidance on prevention.
View Article and Find Full Text PDFPurpose: Females are at increased lifetime risk of stroke and experience worse outcomes compared with males. Tryptophan metabolism through the kynurenine pathway, resulting in decreased tryptophan concentrations, is associated with poor outcomes (larger infarct volume, higher National Institutes of Health Stroke Scale [NIHSS] score, and increased early mortality). This metabolic pathway activity varies by sex in healthy adults.
View Article and Find Full Text PDFArticle Synopsis
- This study investigates the range of skin conditions in patients with germline SUFU pathogenic variants (PVs), focusing on their clinical and histopathologic features.* -
- Conducted across U.S. dermatology and genetics clinics over eight years, the study analyzed skin biopsy samples from five female patients aged 31-68, identifying several types of skin tumors.* -
- Findings reveal that alongside typical basal cell carcinomas, these patients exhibit various indolent skin lesions, indicating a broader range of cutaneous manifestations associated with SUFU PVs.*
Background: Congenital aortic and truncal valve disease is challenging in infants and children given the lack of available prostheses in very small sizes and the limited durability of homograft aortic valve replacement.
Methods: A comprehensive literature search was performed using the PubMed database. Studies were included either if the report included patients less than 1 year of age or if the technique was tailored to accommodate for somatic growth.