Asphalt, widely used in infrastructure, emits complex chemical mixtures throughout its service life, posing significant risks to human health and the environment. This expanded understanding extends the concern from a construction-related hazard to a broader public health issue, especially affecting vulnerable populations like children who play on blacktop surfaces. Despite increased awareness, the specific mechanisms behind asphalt emissions, their impact on asphalt deterioration, and their effects on the human nervous system remain poorly understood.
View Article and Find Full Text PDFObjective: This study investigates the effectiveness of a newly developed smartphone-based application for teaching population oral health needs assessment to undergraduate dental students.
Methods: Target population in this study consisted of all students of Shahid Beheshti School of dentistry in the 7 and 8 semesters in the year 2023. The intervention group (7 semester) received teaching about population oral health needs assessment based on the book "Oral health surveys; basic methods", by means of an application, while the control group (8 semester) received the same content through self-learning activity.
Sulfur mustard (SM), a chemical weapon used in the Iraq-Iran war, can pose severe health risks, especially to the lungs. Dysregulation of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) have been implicated in various inflammatory lung diseases. This study compares the levels of MMPs and TIMPs in the serum and sputum of veterans with serious lung complications to a control group.
View Article and Find Full Text PDFChronic kidney disease (CKD) is a prevalent health condition characterized by gradual kidney function loss. Early detection is crucial for the effective management and treatment of CKD. A promising biomarker for various diseases, including chronic kidney disease, is microRNAs (miRNAs), which are becoming increasingly important due to their stability and differential expression in various disease-related states, including CKD.
View Article and Find Full Text PDFBackground: Resistance to chemo- and radiotherapy is the main obstacle in cancer treatment success, which results in cancer's poor prognosis. Therefore finding the exact mechanism of resistance may contribute to addressing this concern. This could result in improved cancer prognosis and survival outcomes for cancer patients by targeting the basic causes of resistance.
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