Publications by authors named "H M Erdogan"

Background: The aim of this study is to examine the hematological and biochemical variables in patients diagnosed with cancer-related stroke who have different types of cancer and to evaluate the effects of these variables.

Methods: This retrospective study was conducted at a tertiary hospital stroke center and included 153 patients diagnosed with cancer-related stroke. Comprehensive etiological investigations were performed, and patients were classified according to the Trial of Org 101072 in Acute Stroke Treatment (TOAST) classification.

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Article Synopsis
  • - The study explores sigma methodology in clinical laboratories to assess process performance and improve patient safety by identifying performance gaps through sigma metrics and quality target index (QGI) values from internal quality control data in coagulation tests.
  • - Sigma levels are classified as "world-class," "good," or "unacceptable" based on a formula involving total allowable error (TEa) and coefficient of variation (CV), while QGI values help pinpoint issues in accuracy or precision, guiding necessary improvements.
  • - Results indicated that both prothrombin time (PT) and activated partial thromboplastin time (APTT) tests had sigma values below 3, signaling low quality; subsequent actions for improvement were deemed necessary for the laboratory's coagulation parameters
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Melanoma, a type of cancer, has the ability to metastasize and can be fatal. The lack of success in the treatment of melanoma with chemotherapeutic agents and the side effects have led to the search for new agents. Moreover, developing systems that will provide reduce side effects by using biocompatible carriers, may be beneficial.

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Introduction: We aimed to investigate electrophysiologically and histopathologically, the protective effects of intratympanic memantine, an N-methyl-D-aspartate receptor antagonist, on ototoxicity caused by cisplatin, an anti-neoplastic agent used in many types of cancer.

Methods: Thirty-seven guinea pigs with a normal auditory function were randomly allocated to group 1 (cisplatin; n = 8), group 2 (memantine; n = 8), group 3 (cisplatin + memantine; n = 8), group 4 (cisplatin + physiological serum [PS]; n = 8), and group 5 (control; n = 5). Auditory assessments were conducted using distortion product otoacoustic emissions (DPOAE) within a frequency range of 1-32 kHz and auditory brainstem responses (ABRs) within 8-32 kHz.

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Background: Oral isotretinoin is the most effective systemic treatment for acne patients who fail to respond to other forms of therapies. However, hesitations and concerns regarding its side effect profile may detain the patients from treatment. This study aimed to develop and validate the Isotretinoin Hesitancy Scale (IHS) among acne patients.

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