Publications by authors named "H M Branson"
Article Synopsis
- Neonatal hypoxic-ischemic encephalopathy is a severe brain condition in infants, often leading to death or developmental issues, and MRI is used for prognosis, but with high variability in predictions.
- Researchers developed an automated method to analyze MRI data from 286 infants, incorporating anatomical templates and advanced measurements to enhance outcome predictions.
- The study found that MRI-based analysis could predict neurodevelopmental outcomes more accurately than traditional demographic and lab data alone, indicating that machine learning can significantly improve prognosis for affected infants.
Article Synopsis
- The study focused on neonates with perinatal hypoxic-ischemic encephalopathy, comparing two groups: one receiving reoriented care and another with standard care.
- Results showed that infants in the reoriented care group had worse clinical outcomes and electrographic findings, with higher injury scores on cranial ultrasounds and MRI.
- Overall, the findings suggest that reorientation of care may lead to more severe brain injury and clinical challenges in these infants.
Objective: The hippocampus plays a critical role in cognitive networks. The anterior hippocampus is vulnerable to early-life stress and socioeconomic status (SES) with alterations persisting beyond childhood. How SES modifies the relationship between early hippocampal development and cognition remains poorly understood.
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- Early-life nutrition, particularly the intake of mother's milk, plays a significant role in the brain development of preterm-born children, specifically in areas related to processing speed.
- A study involving 40 five-year-old children who were born preterm showed that while general macronutrient intake had no impact, higher consumption of mother's milk was linked to increased volumes in critical brain regions.
- The findings suggest that mother's milk may support better processing speed by enhancing brain structure in these vulnerable children, highlighting the need for further research on nutritional strategies to improve outcomes for preterm infants.