Publications by authors named "H M Al-Mekhlafi"
First report of Leishmania tropica in domestic and wild animal hosts in hyperendemic areas of human cutaneous leishmaniasis in western Yemen: a neglected tropical disease needing One Health approach.
Parasitol Res
June 2024
Article Synopsis
- Cutaneous leishmaniasis (CL), caused mainly by Leishmania tropica, is a significant public health issue in Yemen, prompting a study on the distribution of Leishmania parasites in local animal populations.
- The research involved collecting blood and skin samples from 122 domestic and wild animals in Yemen's Utmah District, using molecular techniques to detect L. tropica DNA.
- Results showed a 16.4% infection rate in various animals, with the majority of haplotypes shared between animals and humans, indicating a potential role of these animals in transmitting CL and highlighting the need for a One Health approach to manage the disease.
Knowledge, attitude, practices and treatment-seeking behaviour concerning cutaneous leishmaniasis among rural hyperendemic communities in western Yemen.
Sci Rep
June 2024
Article Synopsis
- Cutaneous leishmaniasis (CL) is a significant public health issue in rural Yemen, highlighting the importance of understanding local beliefs and practices regarding the disease for effective control measures.
- A study conducted in the Utmah District revealed that while all participants were aware of CL, only 9.3% associated it with sandflies, and many lacked knowledge about preventive measures and had low positive attitudes toward prevention practices.
- Key factors influencing knowledge and practices about CL included age, sex, household cases, residence, occupation, and income, indicating a need for targeted health education and community outreach to improve awareness in these at-risk populations.
Background: The present systematic review and meta-analysis investigated the available evidence about the adherence of Candida Albicans to the digitally-fabricated acrylic resins (both milled and 3D-printed) compared to the conventional heat-polymerized acrylic resins.
Methods: This study followed the guidelines of the Preferred Reporting Items for Systematic Review and Meta-analyses (PRISMA). A comprehensive search of online databases/search tools (Web of Science, Scopus, PubMed, Ovid, and Google Scholar) was conducted for all relevant studies published up until May 29, 2023.
Microsatellite-based analysis reveals populations in the Kingdom of Saudi Arabia result from colonization by both the ancestral African and the global domestic forms.
Evol Appl
February 2024
(Linnaeus, 1762) mosquito is the main vector of dengue, chikungunya and Zika and is well established today all over the world. The species comprises two forms: the ancestral form found throughout Africa and a global domestic form that spread to the rest of the tropics and subtropics. In Saudi Arabia, has been known in the southwest since 1956, and previous genetic studies clustered from Saudi Arabia with the global domestic form.
View Article and Find Full Text PDFA disfiguring neglected tropical disease sweeps war-torn Yemen: a community-based study of prevalence and risk factors of cutaneous leishmaniasis among rural communities in the western highlands.
Trans R Soc Trop Med Hyg
December 2023
Article Synopsis
- - Cutaneous leishmaniasis (CL) is a serious health issue in Yemen, particularly in rural areas, with a study in Utmah district revealing that 33% of participants showed signs of CL, including active skin lesions or scars.
- - The study analyzed 612 participants, identifying 53 cases of active CL confirmed through molecular testing, primarily caused by Leishmania tropica.
- - Key risk factors for CL included being younger than 10, female, living in poorly maintained houses, having family members with skin infections, and sleeping outdoors, while keeping livestock indoors appeared to reduce risk.