Publications by authors named "H Liley"
Article Synopsis
- The eighth annual summary from the International Liaison Committee on Resuscitation (ILCOR) focuses on the latest findings in cardiopulmonary resuscitation (CPR) and emergency cardiovascular care, building on a comprehensive review from 2020.
- This summary is based on the evaluation of recent resuscitation evidence by experts from six different ILCOR task forces, who utilized specific criteria to assess the quality of evidence and reached consensus treatment recommendations.
- The document also identifies key areas where more research is needed, sharing insights into the task forces’ discussions through sections like Justification and Evidence-to-Decision Framework Highlights.
This is the eighth annual summary of the International Liaison Committee on Resuscitation International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations; a more comprehensive review was done in 2020. This latest summary addresses the most recent published resuscitation evidence reviewed by the International Liaison Committee on Resuscitation task force science experts. Members from 6 International Liaison Committee on Resuscitation task forces have assessed, discussed, and debated the quality of the evidence, using Grading of Recommendations Assessment, Development, and Evaluation criteria, and their statements include consensus treatment recommendations.
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- * The research reviewed various training approaches, including self-directed learning and simulation-based training, focusing on both technical and non-technical skills among medical trainees and nurses.
- * Out of 26 studies analyzed, most utilized multiple training methods, with simulation-based training frequently employed; however, issues with skill transfer from simulation to real clinical environments and long-term retention of skills were noted.
Introduction: We showed in a phase II randomised controlled trial (RCT) that oral sildenafil citrate in term labour halved operative birth for fetal distress. We outline the protocol for a phase III RCT (can ntrapartum ildnafil safely vert the isks of ontraction-induced ypoxia? (iSEARCH)) of 3200 women in Australia to assess if sildenafil citrate reduces adverse perinatal outcomes related to intrapartum hypoxia.
Methods And Analysis: iSEARCH will enrol 3200 Australian women in term labour to determine whether up to three 50 mg oral doses of sildenafil citrate versus placebo reduce the relative risk of a primary composite end point of 10 perinatal outcomes potentially related to intrapartum hypoxia by 35% (from 7% to 4.
Article Synopsis
- - The RidStress 2 trial is a phase III study investigating whether maternal oral sildenafil citrate during labor can reduce the need for emergency caesarean sections due to fetal distress in women with small for gestational age infants.
- - The trial involves 660 women and aims to determine the effect of sildenafil citrate on cesarean rates, along with assessing cost-effectiveness and long-term child neurodevelopment.
- - Ethics approval has been secured, and results will be shared through scientific presentations and publications, with the trial registered with relevant clinical trial authorities.