A re-look at the relevance of TSH and thyroid autoimmunity for pregnancy outcomes: Analyses of RCT data from PPCOS II and AMIGOS.

Objective: We examined if thyroid autoimmunity is relevant to the relationship between maternal TSH levels and pregnancy outcomes.

Design: Retrospective cohort analysis of data from two randomized controlled trials (RCTs).

Subjects: Participants of the Pregnancy in Polycystic Ovary Syndrome (PPCOS II, n = 746) and the Assessment of Multiple Intrauterine Gestations from Ovarian Stimulation (AMIGOS, n = 832 with unexplained infertility) RCTs.

Placental site nodules and reproductive outcomes: a clinicopathologic case series.

Background: Placental site nodules (PSNs) are benign tumor-like growths that develop from chorionic-type intermediate trophoblastic cells. Their clinical significance is unknown. This study aims to determine the risk factors associated with PSNs, with focus on possible reproductive impact.

Preimplantation genetic testing for aneuploidy is associated with reduced live birth rates in fresh but not frozen donor oocyte in vitro fertilization cycles: an analysis of 18,562 donor cycles reported to Society for Assisted Reproductive Technology Clinic Outcome Reporting System.

Objective: To evaluate the impact of preimplantation genetic testing for aneuploidy (PGT-A) on first transfer live birth rate (LBR) and cumulative LBR (CLBR) in donor oocyte in vitro fertilization (IVF) cycles.

Design: Retrospective cohort study of the Society for Assisted Reproductive Technology Clinic Outcome Reporting System database.

Setting: Fertility centers reporting to Society for Assisted Reproductive Technology.

A retrospective comparison of the impact of industry payments on assisted reproductive technology practice and outcomes.

Objective: To determine whether industry payments to physicians are associated with a difference in assisted reproductive technology practices and outcomes.

Design: Retrospective cohort.

Setting: Assisted reproductive technology centers.

Trophectoderm biopsy is associated with lower risks of moderate to extreme prematurity and low birthweights: a national registry cohort study of singleton livebirths from frozen-thawed blastocyst transfers.

Background: Trophectoderm biopsy has become the mainstay assisted reproductive technique performed for preimplantation genetic testing, accounting for 43.8% of embryo transfer cycles in the United States in 2019 alone. Despite its prevalence, data on the obstetric and perinatal outcomes post-trophectoderm biopsy remains sparse and mixed.