Publications by authors named "H Lenzen"
: Inflammatory bowel disease (IBD) affects gastrointestinal function and may alter fecal and flatulence odor (intestinal odor) due to changes in inflammation, the gut microbiome, and metabolism. Investigating the relationship between dietary habits and intestinal odor in IBD is critical given the relationship between diet, gut health, and microbiome diversity. : We performed a cohort analysis of a monocentric, cross-sectional study at a tertiary referral center and compared the perception of fecal and flatulence odor in 233 IBD patients (n = 117 women) with that of 96 healthy controls (HCs) (n = 67 women).
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- Biliary strictures are common after liver transplantation, and when endoscopic techniques fail, percutaneous transhepatic biliary drainage (PTBD) can be an effective alternative.
- A study involving 56 liver transplant recipients showed that PTBD has a high success rate (98%) and can improve various lab indicators, although the risk of subsequent biliary complications depends on the type of stricture present.
- Patients who achieved internal drainage into the small intestine had better 12-month survival rates compared to those needing external drainage, highlighting the importance of the initial PTBD approach.
Background: Since diet is generally recognized as an important factor directly modulating the gut microbiome, it is also considered a potential environmental triggering factor for the pathogenesis and onset of inflammatory bowel disease (IBD). While the habitual and sex-related dietary behavior of the general population has been the subject of extensive study and reporting, data on IBD patients' dietary behavior and especially its sex-related differences are underrepresented. However, as diet is an important factor in the course of IBD, we hypothesized that men and women with IBD have a different dietary profile than the general population.
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- The study investigates the safety and significance of transjugular liver biopsy (TJLB) in diagnosing and managing acute liver failure (ALF) in patients at a transplant center over ten years.* -
- Out of 43 patients studied, TJLB confirmed the suspected causes of ALF for most, but was particularly impactful in cases where treatable conditions like autoimmune hepatitis were suspected, altering treatment plans in these scenarios.* -
- Although the degree of intrahepatic necrosis was shown to be significant in initial analyses, it did not significantly predict survival without a liver transplant when examined in more complex statistical models.*
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- ERCP is a complex medical procedure that carries significant risks, including complications like pancreatitis and bleeding, making specialized training and a high volume of procedures essential for success.
- The success rate of ERCPs is closely tied to the number of procedures performed annually, with studies suggesting that centers performing at least 200 ERCPs per year demonstrate better outcomes.
- Emerging reforms in German hospitals emphasize the need for minimum procedure volumes in specialized centers, highlighting that high-quality ERCP requires not just frequency, but also the availability of comprehensive resources and support for managing complications.