Publications by authors named "H Lehman"

Repair of thoracic aortic aneurysms has evolved in recent history. Open surgical intervention has largely been replaced with endovascular intervention. However, there are anatomic limitations to thoracic endovascular aneurysm repair.

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Hypogammaglobulinemia is defined as a reduced immunoglobulin level, which can be either primary due to inborn errors of immunity or acquired in the setting of poor antibody production or increased antibody loss. Secondary hypogammaglobulinemia (SHG) should be considered in patients with a history of immunosuppressive therapy, transplant, protein loss syndromes, certain autoimmune conditions, and malignancies, as it can be associated with increased infectious risk. Appropriate history and lab-based screening in these populations can identify SHG allowing treatment and close monitoring as appropriate.

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Article Synopsis
  • The CDC and ACIP endorse COVID-19 vaccination for patients with inborn errors of immunity (IEI), but there's limited knowledge on its safety and impact on infection severity in these patients.
  • A study involving a registry of 1,245 IEI patients across 24 countries was conducted to gather data on vaccination frequency, safety, and effectiveness, revealing that 64.7% were vaccinated, primarily with mRNA vaccines.
  • Results showed that vaccinated patients had significantly lower hospitalization and ICU admission rates when infected with COVID-19, indicating that vaccination is both safe and effective in reducing the severity of the disease in IEI patients.
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  • Depression and anxiety in caregivers and children significantly impact the quality of life (QoL) for children with asthma, particularly ages 7 to 17.
  • A study involving 205 children with asthma found that while demographics accounted for a small portion of QoL variance, both asthma control and mental health symptoms were more influential.
  • Specifically, child anxiety was the strongest predictor of asthma-related QoL, highlighting the necessity to address both emotional health and asthma management for improving overall quality of life in these children.
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