New type of filaments for improved accuracy of multiple sulfur isotope analyses by electron-impact gas-source mass spectrometry.

Rationale: The analysis of the three sulfur stable isotope ratios (S/S, S/S, S/S) is routinely performed by gas-source isotope ratio mass spectrometry (IRMS) on the SF gaseous molecule, collecting SF ions at m/z ~ 127, 128, 129 and 131. High precision and accuracy are commonly achieved owing to a lack of correction because fluorine has only one isotope and the inert nature of the SF molecule. The analysis of the S/S ratio is, however, complicated by the low abundance of S (~0.

Evaluation of the Performance Characteristics of a New POC Multiplex PCR Assay for the Diagnosis of Viral and Bacterial Neuromeningeal Infections.

Point-of-care syndromic PCR (POC SPCR) assays are useful tools for the rapid detection of the most common causative agents of community-acquired infections responsible for meningitis and encephalitis infections. We evaluated the performance characteristics of the new QIAstat-Dx Meningitis/Encephalitis panel (QS) compared to the laboratory reference methods and the POC SPCR Biofire FilmArray Meningitis Encephalitis Panel (FA). Viral (Enterovirus, Parechovirus, HSV-1, HSV-2, HHV-6, VZV) and bacterial ( K1, , , encapsulated , , , , ) pathogens were suspended at low concentrations and tested with the POC SPCR systems.

In Vitro Activity of 22 Antibiotics against Isolates from People with Cystic Fibrosis. Are There New Therapeutic Options?

Bacteria belonging to the genus are increasingly isolated from respiratory samples of people with cystic fibrosis (PWCF). The management of this multidrug-resistant genus is challenging and characterised by a lack of international recommendations, therapeutic guidelines and data concerning antibiotic susceptibility, especially concerning the newer antibiotics. The objective of this study was to describe the antibiotic susceptibility of isolates from PWCF, including susceptibility to new antibiotics.