Fentanyl dosage for preterm infants suggested by a pharmacokinetic, -dynamic, and -genetic model.

Background: Fentanyl is commonly administered for procedural pain management in preterm infants, but target concentrations have not yet been defined.

Methods: To investigate pharmacokinetics (PK), -dynamics (PD), and -genetics (PG), 25 infants (gestational age 23.3-34.