Publications by authors named "H Lackner"
Article Synopsis
- Systemic sclerosis (SSc) is an autoimmune disease that leads to serious lung issues and is characterized by inflammation, fibrosis, and vascular damage.
- This study explored the mineral buffering system in SSc patients by examining T50 (a measure of calcification propensity) and the size of calciprotein particles, finding both indicators were abnormal in SSc patients compared to healthy controls.
- The results suggest that a disrupted mineral buffering system may contribute to disease progression in SSc, particularly correlating lower T50 levels with impaired lung function, highlighting the need for more extensive research on this topic.
Article Synopsis
- The study looked at how a special chest scan before heart surgery helps reduce the chance of stroke in patients with a certain condition.
- It compared two groups of heart surgery patients—one group had the chest scan and the other did not, and the group with the scan had fewer strokes after surgery.
- The researchers concluded that using this type of scan is a good idea for patients at risk because it can change how doctors perform the surgery and keep patients safer.
Background: The excessive cardiovascular mortality of patients with chronic kidney disease (CKD) could be linked to mineral stress, the biological consequence of calcium-phosphate nanoparticle exposure. This study investigated whether zinc is associated with mineral stress markers in CKD.
Methods: inc and T50 (serum calcification propensity) as well as hydrodynamic radius of secondary calciprotein particles (CPP2) were measured in blood donors and CKD patients with/out dialysis.
To investigate the prevalence and effects of genetic variants (GVs) in survivors of thoracic aortic dissection/aneurysm repair. Patients aged 18-80 years who survived follow-up after cardiosurgical or endovascular repair of thoracic aortic aneurysm or dissection at a single tertiary center between 2008 and 2019 and underwent genetic testing were enrolled. The exclusion criteria were age >60 years, no offspring, and inflammatory- or trauma-related pathogenesis.
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- Sedentary behavior (SB) is linked to health issues like obesity and diabetes, and while physical activity (PA) might help, its effects on inflammation and cardiometabolic responses remain unclear.
- A study involving 17 young adults assessed how light-intensity PA snacks (like standing or walking) compared to prolonged sitting affected health markers during an 8-hour work simulation.
- Results showed that light-intensity activities led to significant positive changes in various inflammatory and cardiometabolic markers, indicating potential health benefits over uninterrupted sitting.