Application of Ultrasound to Animal-Based Food to Improve Microbial Safety and Processing Efficiency.

Animal-based foods such as meat, dairy, and eggs contain abundant essential proteins, vitamins, and minerals that are crucial for human nutrition. Therefore, there is a worldwide growing demand for animal-based products. Since animal-based foods are vital resources of nutrients, it is essential to ensure their microbial safety which may not be ensured by traditional food preservation methods.

Revealing Local Structures of Chiral Molecules via X-ray Circular Dichroism.

Chirality is crucial due to its role in biological and chemical systems, where molecular handedness impacts structure and function. Chiral molecules with nonsuperimposable mirror images exhibit distinct biological activities pivotal in drug design and catalysis. This theoretical study explores X-ray circular dichroism (XCD) as a tool for probing the local structures of chiral molecules.

Revealing the reaction path of UVC bond rupture in cyclic disulfides with ultrafast x-ray scattering.

Disulfide bonds are ubiquitous molecular motifs that influence the tertiary structure and biological functions of many proteins. Yet, it is well known that the disulfide bond is photolabile when exposed to ultraviolet C (UVC) radiation. The deep-UV-induced S─S bond fragmentation kinetics on very fast timescales are especially pivotal to fully understand the photostability and photodamage repair mechanisms in proteins.

Osteoporosis and stroke: a bidirectional mendelian randomization study.

Introduction: Numerous observational studies have identified a link between osteoporosis and stroke. However, the causal genetic relationship between these conditions remains unclear. This study employs a two-sample bidirectional Mendelian randomization (MR) approach to ascertain the causal relationship between osteoporosis and stroke.

PRMT5-Mediated ALKBH5 Methylation Promotes Colorectal Cancer Immune Evasion via Increasing CD276 Expression.

Numerous diseases have been connected to protein arginine methylations mediated by protein arginine methyltransferase 5 (PRMT5). Clinical investigations of the PRMT5-specific inhibitor GSK3326595 are currently being conducted, and the results are promising for preventing cancers. However, the detailed mechanism of PRMT5 promoting colorectal cancer (CRC) malignant progression remains unclear.