Publications by authors named "H L Tey"
Article Synopsis
- Trastuzumab (Herceptin) can be given either intravenously (IV) or subcutaneously, and while both have similar effects and safety, their costs differ, especially between outpatient and homecare settings.
- The study aimed to analyze the costs associated with Homecare SC Herceptin compared to IV Herceptin administered in outpatient facilities in Singapore.
- Results showed that Homecare SC Herceptin significantly reduced annual patient costs by about 58-60%, with drug costs being the main driver; thus, switching to Homecare SC Herceptin is financially advantageous.
Fetal immune cell functions during congenital infections are poorly understood. Zika virus (ZIKV) can vertically transmit from mother to fetus, causing nervous system infection and congenital ZIKV syndrome (CZS). We identified differential functional roles for fetal monocyte/macrophage cell types and microglia in ZIKV dissemination versus clearance using mouse models.
View Article and Find Full Text PDFSmall interfering RNA microneedle patches versus silicone sheets in reducing postoperative scars: a randomized single-blinded intraindividually controlled clinical trial.
Delwyn Zhi Jie Lim Yong Yao Chun Faith Nicole Shih Yun Tan Amelia Yuting Monteiro Hui Mei Cheng Hong Liang Tey
Br J Dermatol
December 2024
Article Synopsis
- A study investigated the effectiveness of siRNA-embedded microneedle patches in reducing excessive scar tissue compared to conventional silicone sheets in post-surgical scars.
- The trial involved a random allocation of two-week-old surgical wounds to receive either treatment, and scar volume was measured at 30 and 60 days using high-resolution scanning.
- Results showed that scars treated with microneedle patches had significantly smaller volumes and higher percentage reductions in scar formation compared to those treated with silicone sheets, indicating a potential new approach to scar management.
Article Synopsis
- Herpes zoster results from the reactivation of the varicella-zoster virus, leading to painful, unilateral skin eruptions, with potential complications like eye issues and long-term pain.
- Diagnosis is primarily clinical but can be supported by lab tests; early antiviral treatment can lessen symptoms and duration, while preventative vaccines have high efficacy.
- The article aims to guide healthcare providers in recognizing, diagnosing, and managing herpes zoster, highlighting the importance of awareness due to increased risk in the adult population following the introduction of varicella immunization in 2020.