Geographic patterns and climatic drivers of the mean genus age of liverworts in North America.

Phylogenetic niche conservatism posits that species tend to retain ancestral ecological traits and distributions, which has been broadly tested for lineages originating in tropical climates but has been rarely tested for lineages that originated and diversified in temperate climates. Liverworts are thought to originate in temperate climates. Mean lineage age reflects evolutionary history of biological communities.

Dahuang-Gancao Decoction Ameliorates Testosterone-Induced Androgenetic Alopecia in Mice.

Ethnopharmacological Relevance: Dahuang-Gancao decoction (DGD) is a traditional Chinese medicinal formula that is recorded in the Synopsis of the Golden Chamber, and is widely used to treat damp-heat in the body. Since the pathological factors of androgenetic alopecia (AGA) also reflect damp-heat blockage, DGD has great potential for the treatment of AGA and has been used effectively in clinical practice.

Aim Of The Study: The aim of the study was to investigate whether external application of DGD could promote the activation and proliferation of hair follicle stem cells (HFSCs) and improve AGA through the Wnt/β-catenin pathway.

Inhibition of GPR4 Attenuates the Formation of Abdominal Aortic Aneurysm Through Inhibiting the SP-1/VEGF-A Signaling.

Abdominal aortic aneurysm (AAA) is a severe cardiovascular disease (CVD) that is partly attributable to endothelial dysfunction, inflammatory response, and angiogenesis. G protein-coupled receptor 4 (GPR4), a proton-sensitive G protein-coupled receptor that is abundantly expressed in vascular endothelial cells, has been associated with numerous physiological functions. Nevertheless, its potential involvement in the development of AAA remains unexplored.

Chromatin Accessibility Mediated by CHROMATIN REMODELING 11 Promotes Chilling Tolerance in Rice.

Chromatin remodeling plays a crucial role in controlling gene transcription by modifying chromatin structure. However, the involvement of chromatin remodeling in plant stress responses, especially cold tolerance, through chromatin accessibility remains largely unexplored. Here, we report that rice (Oryza sativa L.

Data-Driven Approach for Designing Eco-Friendly Heterocyclic Compounds for the Soil Microbiome.

Soil microbiota plays crucial roles in maintaining the health, productivity, and nutrient cycling of terrestrial ecosystems. The persistence and prevalence of heterocyclic compounds in soil pose significant risks to soil health. However, understanding the links between heterocyclic compounds and microbial responses remains challenging due to the complexity of microbial communities and their various chemical structures.