Antihypertensive drug-related problems in Vietnamese ambulatory care.

Evidence of antihypertensive drug-related problems (aDRP) is limited in Asian ambulatory care. To better detect aDRP without causing alert fatigue, we investigated whether adding more antihypertensive agents was associated with increasing aDRP risk and factors associated with physician acceptance of aDRP correction. We conducted a cross-sectional study targeting ambulatory prescriptions of Vietnamese patients with hypertension who either received standard therapy (using two or fewer medications, SdT) or standard plus add-on therapy (using more than two medications, SdT + add-on).

Lycopodiaceae herb from Vietnam as a promising medicinal source of natural hupezine and novel huperzine-producing endophytic fungi.

Objectives: (1) To evaluate the potential of producing huperzine (Hup) and anticholinesterase (AChE) activities of nine native Lycopodiaceae species collected in Vietnam; (2) Isolation, identification and characterization of a novel fungus producing both HupA and HupB isolated from Lycopodium casuarinoides Spring.

Results: All methanolic extracts of nine plants showed AChE inhibition from 8.55 to 71.

Cost-effectiveness of monitoring and liver cancer surveillance among patients with inactive chronic hepatitis B.

Patients with chronic hepatitis B infection (CHB) have an increased risk for death from liver cirrhosis and hepatocellular carcinoma (HCC). In the United States, only an estimated 37% of adults with chronic hepatitis B diagnosis without cirrhosis receive monitoring with at least an annual alanine transaminase (ALT) and hepatitis B deoxyribonucleic acid (DNA), and an estimated 59% receive antiviral treatment when they develop active hepatitis or cirrhosis. A Markov model was used to calculate the costs, health impact and cost-effectiveness of increased monitoring of adults with HBeAg negative inactive or HBeAg positive immune tolerant CHB who have no cirrhosis or significant fibrosis and are not recommended by the current American Association for the Study of Liver Diseases (AASLD) clinical practice guidelines to receive antiviral treatment, and to assess whether the addition of HCC surveillance would be cost-effective.

From 0D to 2D: microwave-assisted synthesis of electrically conductive metal-organic frameworks with controlled morphologies.

Morphology control of electrically conductive metal-organic frameworks (EC-MOFs) can be a powerful means to tune their surface area and carrier transport pathways, particularly beneficial for energy conversion and storage. However, controlling EC-MOFs' morphology is underexplored due to the uncontrollable crystal nucleation and rapid growth kinetics. This work introduces a microwave-assisted strategy to readily synthesize Cu-HHTP (HHTP = 2,3,6,7,10,11-hexahydroxytriphenylene) with controlled morphologies.

Diverse perspectives on supporting the health and wellness of people with intellectual and developmental disabilities.

Background: Persons with intellectual and/or developmental disabilities (IDD) are a growing population, frequently living with complex health conditions and unmet healthcare needs. Traditional clinical practice and research methods and measures may require adaptation to reflect their preferences.

Objective: The perspectives of people with IDD, caregivers/partners, and clinicians were obtained to provide insight into factors contributing to the health and wellness of people with IDD.