Purpose: Sex hormones affect development and prognosis of gastric cancer (GC). This study aimed to compare the sex hormone receptor expression between control and GC, and to evaluate its correlation with patient characteristics.
Materials And Methods: 110 patients (74 with GC, 36 controls) underwent immunohistochemistry (IHC) and reverse transcription-polymerase chain reaction (RT-PCR) for estrogen receptors (ERs) α and β and androgen receptor (AR).
This study investigates the application of levan- produced from Paenibacillus polymyxa SG09-12 as an antiviral agent against cucumber mosaic virus (CMV). A high-purity microbial levan was produced and purified using diafiltration. The chemical composition, structure, and functional groups of the levan were characterised using high-performance liquid chromatography (HPLC), nuclear magnetic resonance (NMR), Fourier-transform infrared spectroscopy (FT-IR), and X-ray photoelectron spectroscopy (XPS).
View Article and Find Full Text PDFBacterial cell wall assembly and remodeling require activities of peptidoglycan (PG) hydrolases as well as PG synthases. In particular, the activity of DD-endopeptidases, which cleave the 4-3 peptide crosslinks in PG, is essential for PG expansion in gram-negative bacteria. Maintaining optimal levels of DD-endopeptidases is critical for expanding PG without compromising its integrity.
View Article and Find Full Text PDFElectrocatalytic hydrodeoxygenation (EHDO) is a promising approach for upgrading biomass-derived bio-oils to sustainable fuels without the use of high-pressure hydrogen gas and elevated temperatures. However, direct EHDO for realistic hydrophobic lignin-based oil production remains challenging. Herein, we discuss the molecular dynamics that govern the EHDO of lignin bio-oil over Pt/C in an acidic electrolyte added with 2-propanol or a surfactant.
View Article and Find Full Text PDFClin Exp Otorhinolaryngol
January 2025
Objectives: This study evaluated the cost-effectiveness of using hearing aids among individuals aged 50 and older with varying levels of hearing loss in South Korea.
Methods: A state-transition Markov model was employed to assess the cost-effectiveness of hearing aid utilization from a societal perspective. We simulated a cohort of patients aged 50, tracking their progression through normal, mild, moderate, and severe stages of hearing loss until death or age 80.