Mortality according to a prior assessment of biological age.

Background: Measures of biological age have not been proven to predict mortality. This study examines whether measuring biological age improves the prediction of mortality.

Methods: Prospective study from 1981 to 2001 of 397 male London Civil Servants.

Why do some people look older than they should?

Background: As a component of studies on biological age, the age of subjects from their appearance (perceived age) was estimated.

Objective: To determine the factors associated with looking older.

Methods: Cross sectional study of London civil servants (318 men, 129 women) in the Department of the Environment study.

The relationship between plasma cholesterol concentration and minor psychiatric disturbance in the Department of the Environment Study.

We examined the hypothesis that low plasma cholesterol concentration was associated with minor psychiatric disturbance in a cross-sectional study of 410 male and 138 female civil servants. Psychiatric disturbance was measured using the 30-item General Health Questionnaire (GHQ). Mean GHQ score did not vary significantly with quartile of total cholesterol concentration.

Quality of life in treated hypertension: a case-control community based study.

The aim of this case-control community study was to determine whether there was a difference in quality of life between hypertensive subjects and matched normotensive controls. Cases aged 40-79 years were randomly selected from a hypertensive register and matched with controls for age, sex, ethnicity and health centre. Cases had phase V diastolic blood pressure (DBP) > or = 100 mm Hg or systolic blood pressure (SBP) > or = 180 mm Hg, or were on anti-hypertensive medication.

Changing trends in the epidemiology of malignant melanoma: gender differences and their implications for public health.

Background: Skin cancer has been identified as a key area in the English health strategy. Review of trends in the epidemiology of melanoma by age, sex and social class can contribute to ensuring that preventive efforts are targeted appropriately and subsequently to monitoring the effects of campaigns.

Methods: Descriptive epidemiological study using data for both sexes from cancer registrations by age (England & Wales 1971-1989), and from mortality statistics by age (England & Wales 1951-1970, England 1969-1992) and by social class (England & Wales 1970-1972 for men and women, England & Wales 1979-1980, 1982-1983 for men and Great Britain 1979-1980, 1982-1983 for women).