Publications by authors named "H L Cole"

Light pollution disrupts the natural dark-light rhythmicity of the world and alters the spectral composition of the nocturnal sky, with far-reaching impacts on natural systems. While the costs of light pollution are now documented across scales and taxa, community-level mitigations for arthropods remain unclear. To test two light pollution mitigation strategies, we replaced all 32 streetlights in the largest visitor center in Grand Teton National Park (Wyoming, USA) to allow wireless control over each luminaries' color and brightness.

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Injuries associated with contemporary life, such as automobile crashes and sports injuries, can lead to large numbers of traumatic neuromuscular injuries that are intimately associated with bone fractures. Regulatory and non-coding RNAs play essential roles in multiple cellular processes, including osteogenic differentiation and bone healing. In this review, we discuss the most recent advances in our understanding of the regulatory and non-coding RNA biology of osteogenic differentiation in stem, stromal and progenitor cells.

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Background: Public toilets enable populations, including those who menstruate, to move through public spaces. Menstrual Friendly Public Toilets (MFPT) are accessible, safe, and clean public toilets that provide those who menstruate the space and resources to navigate cities with dignity and comfort. However, there is little evidence on the status of MFPTs in urban centers.

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Article Synopsis
  • Researchers developed and studied five new iridium(III) complexes with thienyl groups to improve their performance in photodynamic therapy for cancer.
  • They found that the number of thienyl units affected the complexes' light absorption and emission properties, shifting them to longer wavelengths, which is beneficial for therapy.
  • In tests against melanoma and breast cancer cell lines, one complex showed significant photocytotoxicity when activated by visible light, remaining effective even under low-oxygen (hypoxic) conditions.
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