Publications by authors named "H Kunimoto"
Anemia is a major clinical manifestation seen in myelodysplastic syndromes (MDS). Treatment options for anemia in low-risk MDS are limited. Especially, oral medication which is uniformly effective for anemia in low-risk MDS is required.
View Article and Find Full Text PDFBackground: The cause of chronic thromboembolic pulmonary hypertension (CTEPH) remains largely unknown. Recently, clonal hematopoiesis (CH) has been reported to be associated with cardiovascular and thromboembolic diseases. Here, we investigated the prevalence and clinical impact of CH in patients with CTEPH.
View Article and Find Full Text PDFObjectives: Coronary flow reserve (CFR) is a strong predictor of cardiovascular events and prognosis in patients with coronary artery disease. This study aimed to evaluate preoperative factors associated with the unsuccessful restoration of CFR after coronary artery bypass grafting (CABG).
Methods: Included in this study were the 65 patients who presented with functionally significant left anterior descending artery (LAD) lesions confirmed by both fractional flow reserve (FFR) and instantaneous wave-free ratio (iFR), and who underwent successful CABG at our hospital within the study period.
Article Synopsis
- - Erdheim-Chester disease (ECD) is a rare condition marked by the abnormal accumulation of histiocytes in various body systems, often leading to complications like pericardial effusion and thickening, resulting in potential heart issues.
- - A case study is presented of a 51-year-old man with ECD who developed severe constrictive pericarditis, experiencing symptoms like fluid retention and heart failure.
- - Following an accurate diagnosis, the patient was treated with interferon alpha, leading to significant improvements and emphasizing the need for early intervention for unexpected ECD complications.
Aim: Short-term use of pemafibrate (PEM), a selective modulator of peroxisome proliferator-activated receptor alpha, has been reported to improve abnormal liver function in patients with nonalcoholic fatty liver disease with hypertriglyceridemia (HTG-NAFLD). This study aimed to clarify the effects and predictive factors of long-term 72-week PEM administration on body composition, and laboratory tests in HTG-NAFLD patients.
Methods: Fifty-three HTG-NAFLD patients receiving a 72-week PEM regimen were retrospectively enrolled.