Publications by authors named "H Kumata"

In laparoscopic intersphincteric resection, identifying the dissection layer near the anus is often difficult. We safely proceeded with it, using indocyanine green-containing gauze on the anal side to remove the internal anal sphincter with indocyanine green fluorography.

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Prostatic and colon carcinomas with neuroendocrine differentiation are reported to behave more aggressively than those without such differentiation. In hepatocellular carcinomas (HCCs), however, only a few studies have reported the expression status of neuroendocrine markers and somatostatin receptor 2, the main target of a somatostatin analog. Furthermore, the prognostic significance of the markers in HCCs has not been fully explored.

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Background: In living-donor kidney transplantation, laparoscopic nephrectomy from a donor has become widespread. However, more careful treatment is required for nephrectomy from a donor with horseshoe kidney. This report presents an interesting surgical case of laparoscopic nephrectomy from a donor with horseshoe kidney.

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Article Synopsis
  • SCAP plays a crucial role in cholesterol metabolism by activating SREBP transcription factors in response to low cholesterol levels, leading to gene expression for cholesterol synthesis.
  • In cholesterol-rich conditions, SCAP interacts with the VAP-OSBP complex at ER-Golgi membrane contact sites to transport cholesterol and phosphatidylinositol 4-phosphate (PI4P), affecting lipid turnover.
  • Knocking down SCAP disrupts the distribution of the VAP-OSBP complex and hinders the formation of transport carriers (CARTS) necessary for Golgi function, which can be reversed by restoring SCAP function.
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Potential risks of polycyclic aromatic hydrocarbons (PAHs) in sediments of a Japanese bay contaminated by carbon manufacturing plant effluent were evaluated by calculating toxicity units (TUs). TUs calculated from the measured whole-sediment concentrations (C) were often higher than or close to 1, signaling a possible toxicity concern to benthic organisms. In contrast, TUs based on the freely dissolved pore water concentrations (C) measured by an ex-situ passive sampling method with polyethylene strips were 0.

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