Publications by authors named "H Koyanagi"

Extracellular vesicles (EVs) play important roles in intercellular communication in various biological events. In particular, EVs released from cancer cells have attracted special attention. Although it has been reported that cancer-associated glycosphingolipids play important roles in the enhancement of malignant properties of cancer cells, the presence, behavior, and roles of glycosphingolipids in EVs have not been elucidated.

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  • The study aimed to assess the prevalence of constipation among hospitalized patients, including the prevalence of associated symptoms and factors contributing to constipation.
  • The research was based on a retrospective cohort analysis conducted over one day at a university hospital, focusing on inpatients who had been there for at least three days and examining their nursing records for specific symptoms and nutritional intake.
  • Results showed 12.2% prevalence of constipation, particularly high in the Psychiatry Department at 64.1%, with pre-admission constipation being a significant factor linked to post-admission constipation.
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  • * The patient group consisted of nearly equal numbers of men and women, with a mean age of 62 years, and the UE procedures were performed by various types of surgeons, including plastic, orthopedic, and general surgeons.
  • * Results showed high rates of inappropriate surgical techniques, with many patients requiring re-excisions and subsequent soft-tissue reconstruction, highlighting the need for improved education on sarcoma management for all surgeons.
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Purpose: Perivascular epithelioid cell tumors (PEComas) of the bone and soft tissues are rare mesenchymal neoplasms, some of which are malignant. However, their clinical and pathological characteristics remain unclear. This study was performed to investigate the clinical and pathological characteristics of PEComas in bone and soft tissues by leveraging information from the Japanese Musculoskeletal Oncology Group.

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  • * The study analyzed 42 patients on BMAs, focusing on radiographic signs of AFF and found that 42.9% exhibited some form of cortical thickening, particularly linked to the duration of BMA use.
  • * Results showed that the longer patients used BMAs, the greater the prevalence of AFF signs, suggesting that regular screening might be necessary for asymptomatic patients on long-term treatment.
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