Publications by authors named "H Koval"

This research was conducted at Bukovinian State Medical University and the Centre of Reproductive Medicine and included a total of 30 infertile women. The control group consisted of 10 women with tubal infertility resulting from a prior history of inflammation, who, following a comprehensive clinical and laboratory assessment, exhibited no other underlying health conditions and could be regarded as essentially healthy individuals. Participants in the control group ranged from 21 to 42 years, with an average age of 29.

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Objective: The aim: To study the determination of Mesothelin level in women with endometriosis associated with infertility and estimate influence of probiotic on endometriosis according of Mesothelin level in complex preparation before assisted reproductive technologies.

Patients And Methods: Materials and methods: In this study, we conducted a retrospective analysis of the medical records of 40 infertile women who underwent assisted reproductive technologies while also using the probiotic "Femina Probiz." We divided the participants into two groups.

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Objective: The aim: To identify clinical and epidemiological features of meningococcal infection on the initial day of a patient's medical consultation, as well as the efficacy of laboratory examinations.

Patients And Methods: Materials and methods: A retrospective analysis of 76 patients' histories diagnosed with meningococcal disease was carried out.

Conclusion: Conclusions: Patients in the Transcarpathian region mainly develop an atypical form of meningococcal disease.

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Article Synopsis
  • The study aimed to evaluate the Nlrp3 inflammasome expression in the blood of women with endometriosis-related infertility and explore the effects of a probiotic treatment before assisted reproductive technologies.
  • The research involved 30 infertile women, divided into a main group with endometriosis who received a specific probiotic and a control group of women with tubal infertility who did not take probiotics.
  • Researchers used RT-PCR to analyze the gene expression of Nlrp3-inflammasome in the blood samples before and after the probiotic treatment, finding significant differences in expression levels that could influence reproductive outcomes.
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Despite several targeted antiviral drugs against SARS-CoV-2 currently being available, the application of type I interferons (IFNs) still deserves attention as an alternative antiviral strategy. This study aimed to assess the therapeutic effectiveness of IFN-α in hospitalized patients with COVID-19-associated pneumonia. The prospective cohort study included 130 adult patients with coronavirus disease (COVID-19).

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