Publications by authors named "H Koguchi-Yoshioka"

Local immune memory develops at the site of antigen exposure and facilitates a rapid and strong local adaptive defense upon re-exposure. Resident memory T (T) cells play a role in local immune memory, and their cell-surface molecules CD69 and CD103 promote their tissue residency. However, the contribution of these molecules to skin immune memory remains unclear.

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Article Synopsis
  • * Researchers used single-cell RNA sequencing to analyze cells from both cNF and pNF in the same patient, finding distinct transcriptional profiles for each type.
  • * Their results showed that pNF has characteristics more akin to malignant tumors, including specific types of cells like Schwann cells and macrophages, while cNF contains more CD8 T cells, suggesting important differences in their cellular environments and behaviors.
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