Interferometric sphere surface metrology with cylindrical reference for precision topography.

We demonstrate a method for measuring a surface map of a spherical body with interferometric optical point sensors while rotating the test subject. The setup takes advantage of the excellent performance of heterodyne interferometry at nanometer levels and suppression of common-mode errors, as a cylindrical mirror mounted adjacent to the sphere is used as a reference. Future space based missions for gravitational wave research demand an improved inertial reference sensor with reduced acceleration noise levels.

Interferometric surface mapping of a spherical proof mass for ultra precise inertial reference sensors.

In the context of our investigations on novel inertial reference sensors for space applications, we have explored a design utilizing an optical readout of a spherical proof mass. This concept enables full drag-free operations, hence reducing proof mass residual acceleration noise to a minimum. The main limitations of this sensor are errors in position determination of the center of mass of the proof mass due to the surface topography and the involved path length changes upon rotation.

Interferometric characterization and modeling of pathlength errors resulting from beamwalk across mirror surfaces in LISA.

An alternative payload concept with in-field pointing for the laser interferometer space antenna utilizes an actuated mirror in the telescope for beam tracking to the distant satellite. This actuation generates optical pathlength variations due to the resulting beamwalk over the surface of subsequent optical components, which could possibly have a detrimental influence on the accuracy of the measurement instrument. We have experimentally characterized such pathlength errors caused by a λ/10 mirror surface and used the results to validate a theoretical model.

Keratinocyte-derived follistatin regulates epidermal homeostasis and wound repair.

Activin is a growth and differentiation factor that controls development and repair of several tissues and organs. Transgenic mice overexpressing activin in the skin were characterized by strongly enhanced wound healing, but also by excessive scarring. In this study, we explored the consequences of targeted activation of activin in the epidermis and hair follicles by generation of mice lacking the activin antagonist follistatin in keratinocytes.