Publications by authors named "H Kodaira"
In February 2024, a 22-year-old Japanese resident of Osaka Prefecture was diagnosed with measles in the PCR test. He had flown from Dubai to Osaka Kansai International Airport. We finally detected 13 incident measles cases identified as infected by the index case and collected data on these individuals to evaluate the association between vaccination and incubation period.
View Article and Find Full Text PDFBackground: At present, eradication regimens for non-Helicobacter pylori Helicobacter (NHPH) have not been established yet. We investigated effectiveness of the standard triple-drug combination therapy for Helicobacter pylori eradication and of a proton pump inhibitor (PPI) monotherapy in eradication of NHPH.
Methods: Subjects were the patients who were diagnosed with NHPH-infected gastritis based on microscopic findings, helical-shaped organisms obviously larger than Helicobacter pylori, in the gastric mucosal specimens using Giemsa staining at Kenwakai Hospital between November 2010 and September 2021, whose NHPH species were identified by polymerase chain reaction (PCR) analysis of urease genes in endoscopically-biopsied samples, and who consented to NHPH eradication with either the triple-drug combination therapy for one week or a PPI monotherapy for six months.
Background: Non-Helicobacter pylori Helicobacter (NHPH) is rarely detected in duodenal mucosa due to its preference for slightly acidic environments. Here, we report four cases of NHPH-infected gastritis with duodenal spiral bacilli, potentially NHPH, indicating the possibility of duodenal mucosal infection.
Case Presentation: In every case, gastric mucosa showed endoscopic findings characteristic of NHPH-infected gastritis, and a mucosal biopsy was taken from the duodenal bulb; spiral bacilli were identified under microscopy using Giemsa staining.
Article Synopsis
- * It highlights new guidance developed by a working group on managing heat stroke amidst the COVID-19 pandemic, incorporating updated research from multiple sources.
- * The second edition of this guidance focuses on critical aspects such as indoor ventilation, mask safety, and the isolation of older adults, aiming to improve prevention and treatment strategies for heat stroke during the ongoing pandemic.
Article Synopsis
- * Researchers successfully created chemically modified mannose-siRNA (CMM-siRNA) that selectively binds to CD206, allowing targeted delivery to macrophages and dendritic cells.
- * The CMM-siRNA demonstrated effective gene silencing and protein reduction in these cells, suggesting significant potential for advancing siRNA-based therapies and targeting other cell types in the future.