Publications by authors named "H Knobel"

Introduction: People with HIV (PWH) with poor immune response despite adequate antiretroviral treatment (ART) are susceptible to non-AIDS-related health issues. This study seeks to evaluate bone quality in Immunological Non-Responders (INRs) in comparison to those with proper immune response (IRs) using in vivo microindentation to quantify bone quality, in addition to conventional bone mineral density (BMD) evaluations.

Methods: A cross-sectional study was conducted at Hospital del Mar in Barcelona from January 2019 to June 2023.

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Article Synopsis
  • A study was conducted to create a risk score to predict loss to follow-up (LTFU) in patients living with HIV (PLWH) in Catalonia and the Balearic Islands.
  • The study analyzed 6,661 PLWH and identified key factors contributing to LTFU, including age, nationality, drug use, viral load, and time since diagnosis.
  • The results indicated that a significant portion of PLWH (28.8%) was at medium risk and 3.4% at high risk for LTFU, highlighting the need for targeted interventions to retain patients in HIV care.
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Background: People with HIV have a substantially higher risk of anal cancer than the general population. We aimed to identify risk factors associated with the development of anal cancer among people with HIV to implement more effective and targeted screening strategies.

Methods: We conducted a multicentre retrospective cohort study in 16 hospitals across Catalonia and the Balearic Islands, Spain, between Jan 1, 1998, and Dec 31, 2022.

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Objectives: People living with HIV (PLWH) are common users of complementary and alternative medicine (CAM). The main objective of this study was to study the frequency and patterns of CAM natural products use in a large cohort of PLWH and to identify potential drug-drug interactions (DDIs) and the impact on their antiretroviral treatment (ART) adherence and efficacy.

Methods: This was a cross-sectional multicenter survey including 420 PLWH from different Spanish hospitals.

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Article Synopsis
  • * The study analyzed cause of death using a modified protocol and found a significant decrease in all-cause mortality rates, dropping from 9.6 per 1000 person-years to 3.33. Major causes of death now include non-AIDS cancers, cardiovascular disease, and liver diseases.
  • * Key predictors for both AIDS and non-AIDS mortality included factors like age, comorbidities, and ART adherence,
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