Publications by authors named "H Knegtering"
Psychedelics as a potential treatment for tobacco use disorder: a systematic review.
Discov Ment Health
September 2024
Introduction: Despite considerable efforts, tobacco use disorder persists as a significant public health issue. The effectiveness of current smoking cessation therapies is limited, leading to a growing interest in alternative treatment approaches such as psychedelics.
Aim: The aim of this review is to evaluate the scientific evidence regarding the role of psychedelics in smoking cessation.
Apathy is a core negative symptom associated with an unfavorable functional outcome. Noninvasive brain stimulation has shown promise in the treatment of schizophrenia but has not been tested specifically for apathy. We conducted a randomized controlled trial of intermittent theta-burst (iTBS) transcranial magnetic stimulation and transcranial direct current stimulation (tDCS) targeted at the right dorsolateral prefrontal cortex (DLPFC) in patients diagnosed with a psychotic disorder suffering from apathy.
View Article and Find Full Text PDF[Muscarinic M1 and/or M4 receptor agonists as potential novel treatments for psychoses].
Tijdschr Psychiatr
November 2023
Article Synopsis
- Research indicates that cholinergic muscarinic 1 (M1) and 4 (M4) receptors may play a role in psychotic disorders, suggesting that targeting these receptors could lead to new treatment options.
- The study aims to review existing literature on these receptors and the potential impact of new drugs like xanomeline and emraclidine on treating psychosis.
- Findings showed reduced presence of M1 and M4 receptors in specific brain areas linked to schizophrenia, with initial drug trials displaying promise in improving cognitive function and other symptoms, though further research is necessary to confirm their effectiveness and safety.*
Cultural competence of mental health practitioners in the Netherlands.
Int J Soc Psychiatry
March 2024
Background: The importance of providing mental health from a transcultural perspective in establishing a therapeutic alliance is recognized. However, it is currently unknown how many mental health practitioners in the Netherlands feel capable of providing mental healthcare from a transcultural perspective, or if they are familiar with the Cultural Formulation Interview (CFI). The CFI is a tool used in mental health care to gather culturally relevant patient information, enhancing cultural sensitivity in treatment.
View Article and Find Full Text PDFBackground: Choline is an essential micronutrient important for fetal brain development. Research suggests that maternal choline supplementation during pregnancy may reduce the risk of developing neuropsychiatric disorders such as psychosis in offspring.
Aim: To provide a narrative review of evidence from the literature for the possible prevention of neuropsychiatric problems such as psychosis by maternal choline supplementation.