[Primary squamous cell carcinoma of the thyroid gland].

Primary squamous cell carcinoma of the thyroid gland is a rare form of cancer. As part of the differential diagnosis, metastases or direct extension from an extra-thyroidal primary tumor must always be ruled out. We report on a 59-year-old patient presenting with a 3.

[Surgical management of persistent diarrhea].

An 82-year-old patient presented with a cervical lesion and refractory diarrhea of many years' standing. Surgical therapy of a medullary thyroid carcinoma had been performed 16 years previously. Appropriate tumor follow-up had not been carried out hitherto.

Subset of esophageal adenocarcinoma expresses adhesion molecule l1 in contrast to squamous cell carcinoma.

Background: Esophageal adenocarcinoma is currently the most rapidly increasing cancer in Western populations. L1 (CD171), a neural cell adhesion molecule, has an essential function in tumor progression and has been shown to be expressed in the proliferating cells of the intestinal crypts in mice. The aim of the current study was to determine L1 expression in esophageal cancer and to evaluate whether L1 could serve as a potential marker and therapeutic target for this tumor type.

The role of vascular adhesion molecules PECAM-1 (CD 31), VCAM-1 (CD 106), E-selectin (CD62E) and P-selectin (CD62P) in severe porcine pancreatitis.

Inflammatory cytokines have been shown to mediate organ damage by their action on vascular endothelia and leukocytes, in part by upregulating the expression of adhesion molecules, which in turn convey transmigration of leukocytes into tissue. The upregulation and activation of vascular cell adhesion molecules on the endothelial cells avail firm leukocyte adhesion to the vascular endothelium and enhance their transmigration and consecutive tissue injury. The aim of this study was to evaluate the expression of vascular adhesion molecules CD 31 (PECAM-1), CD 106 (VCAM-1), CD 62E (E-Selectin) and CD 62P (P-Selectin) in the pancreas and distant organs of pigs suffering from acute necrotizing pancreatitis (AP).

Clinical value of loss of heterozygosity in serum microsatellite DNA of patients with gastrointestinal stromal tumors.

Goals: To study the role of loss of heterozygosity (LOH) in serum microsatellite DNA of patients with gastrointestinal stromal tumors (GIST).

Background: In GIST, tumor markers from peripheral blood are missing.

Study: Seventy-eight patients (59 GIST, 13 leiomyomas, 2 leiomyosarcomas, and 4 schwannomas) underwent resection at our institute between 1985 and 2006.