Serum selenium concentration in patients with Wilson's disease.

Background/aims: Wilson's disease is a genetically determined disorder of copper metabolism in the liver. Due to the toxic accumulation of this trace element, body organs are damaged by free radical generation, lipid peroxidase and inhibition of synthesis of some proteins. Behavior of anti-oxidative factors in Wilson's disease has not been completely evaluated yet.

Primary hepatocellular carcinoma in patients with chronic hepatitis B virus infection.

The paper presents 66 hepatocellular carcinoma (HCC) patients (57 males, 9 females) with chronic hepatitis B virus (HBV) infection in the clinical, diagnostic and therapeutic aspects. In 60 cases, hepatic cirrhosis was the primary hepatic disease, in 5--chronic hepatitis, and in 1--neoplasm developed in morphologically normal liver. Forty out of 66 patients were HBsAg seropositive.

[Hepatocellular carcinoma (CHC) in patients chronically infected with HBV].

42 cases of hepatocellular carcinoma (CHC) in patients chronically infected with HBV are presented. These are 37 men and 5 women, aged 12 to 78 years. The underlying disease was liver cirrhosis in 38 cases and chronic active hepatitis in 4.