Publications by authors named "H Khoja"
Orbital leiomyoma originating from Muller muscle: A case report and review of the literature.
Int J Surg Case Rep
November 2024
Article Synopsis
- Orbital leiomyomas can develop anywhere in the orbit, with posterior ones arising from smooth muscle cells in vessel walls and anterior ones from the capsulopalpebral or Muller muscle.
- The case presented involves a 24-year-old man with swelling in the right upper eyelid, an MRI revealing a defined mass in the medial orbital space, and a biopsy confirming the diagnosis.
- This case is notable as it documents the first known orbital leiomyoma originating from the Muller muscle, highlighting a male predominance in similar cases.
A hepatic abscess is a potentially life-threatening condition that can lead to major complications if left untreated. One of the rarest complications of hepatic abscesses is rupture into adjacent organs like the duodenum, stomach, and colon. We report a case of an elderly male patient with a hepatic abscess that ruptured into the duodenum and colon, forming fistulous connections.
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- Malignant mesotheliomas are rare and aggressive tumors that primarily form on mesothelial surfaces, with malignant peritoneal mesothelioma (MPM) often diagnosed at an advanced stage due to vague abdominal symptoms.
- Treatment has evolved from palliative chemotherapy to the more effective combination of cytoreductive surgery (CRS) and bidirectional intraoperative chemotherapy (BDIC), which targets remaining tumor cells effectively.
- A case study of a 51-year-old woman with MPM and chronic kidney disease found successful treatment through CRS-BDIC without complications, suggesting that nephrotoxic drugs like cisplatin and ifosfamide might still be feasible for patients with kidney issues.
Head and neck squamous cell carcinomas (HNSCCs) are a common type of cancer, ranking as the sixth most prevalent cancer worldwide and having a high morbidity and mortality rate. Among oropharyngeal squamous cell carcinoma (OPSCC) cancers, tonsillar squamous cell carcinoma (TSCC) is the most prevalent and has a particularly aggressive clinical course with poor disease outcomes. The tumor microenvironment (TME) of HNSCC is complex and heterogeneous, playing a crucial role in effective cancer therapy.
View Article and Find Full Text PDFIntroduction: Angiosarcoma is a rare and highly aggressive soft tissue malignancy originating from vascular and lymphatic endothelial cells. Epithelioid angiosarcoma is the rarest subtype of angiosarcoma, characterized by the proliferation of large polygonal cells with an epithelioid feature. The occurrence of these tumors in the oral cavity is highly uncommon, and immunohistochemistry staining is essential to differentiate epithelioid angiosarcoma from mimicking lesions.
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