Publications by authors named "H Kaspar"

Background/objectives: Patients requiring haemodialysis often perceive the cost of their travels to the dialysis centres as a significant burden. The study aimed to collect a first Swiss national data set on transport costs and assess their impact on patients and their relatives.

Methods: In addition to interviews with patients, a quantitative survey was developed and distributed online using a voluntary sampling strategy.

View Article and Find Full Text PDF

Antimicrobial susceptibility testing (AST) in the veterinary sector by broth microdilution is mainly based on commercially available microtitre plates with specific panels. A critical review of commercially available microtitre panels identified AST panels that fulfil the requirements for obtaining reliable AST results by covering the necessary antimicrobial concentrations for both clinical breakpoints as well as quality control (QC) ranges for approved QC strains. However, there are AST panels in which these prerequisites are only in part fulfilled, and some AST panels that do not fulfil the aforementioned criteria at all.

View Article and Find Full Text PDF

Parenteral antimicrobial treatment results in the excretion of antimicrobial-resistant bacteria. Dairy cows are commonly housed side by side in tie-stalls and often receive antimicrobial treatment. However, studies investigating treated cows as source of colonization of neighboring cows with resistant bacteria are scarce.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to analyze the macrolide resistance of porcine Pasteurella multocida isolates in Germany from 2008 to 2021.
  • Out of 1114 isolates, only four (0.36%) showed macrolide resistance, with some carrying specific mutations or resistance genes.
  • A new element called Tn7730 was discovered in one isolate from 2021, which contained multiple resistance genes, prompting concerns for future monitoring.
View Article and Find Full Text PDF
Article Synopsis
  • Extended-spectrum cephalosporins (ESCs) are crucial antimicrobials used to combat multidrug-resistant (MDR) bacterial infections, but resistance against them is rising, mainly due to certain β-lactamases produced by Enterobacterales.
  • This study focused on analyzing Escherichia coli strains with resistance genes collected from Canada, France, and Germany over a 14-year period, employing advanced sequencing techniques to examine the transmission of these resistance genes via plasmids.
  • Five distinct plasmid subtypes linked to the spread of ESC resistance genes were identified, with varying prevalence across geographic regions and host species, highlighting the role of plasmid diversity in the global issue of antibiotic resistance.
View Article and Find Full Text PDF