Health-related quality of life of children with Developmental Coordination Disorder.

Background: Although Developmental Coordination Disorder (DCD) is primarily a motor disorder, it can also impact emotional and psychosocial functioning of children with this condition. Evidence suggests that children with DCD experience lower quality of life than their peers, but few studies have explicitly examined the health-related quality of life (HRQOL) of these children.

Aims: To: (1) describe HRQOL of children with DCD compared to typically-developing children; (2) compare HRQOL from the perspectives of children with DCD and their parents; and (3) explore predictors of HRQOL for children with DCD.

Pharmacokinetics and relative bioavailability of tablet of micronized glibenclamide in 4 Chinese healthy men.

Pharmacokinetic characteristics and relative bioavailability of the regular preparation (RG) and micronized preparation (MG) of glibenclamide (Gli) were studied in 4 Chinese healthy men. Each volunteer entered 2 consecutive experiments at the same dose (10.5 mg) of RG and MG tablets given orally.