Oocyte-Secreted Factors Synergize With FSH to Promote Aromatase Expression in Primary Human Cumulus Cells.

Context: The role of growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15) on aromatase regulation is poorly understood in humans.

Objective: Determine GDF9 and BMP15 effects on FSH stimulation of estradiol production in primary human cumulus granulosa cells (GCs). We hypothesized that the combination of GDF9 and BMP15 potentiates FSH-induced aromatase expression.

Critical analysis and mapping of research trends and impact assessment of polyaromatic hydrocarbon accumulation in leaves: let history tell the future.

The article is basically an attempt to provide a consolidated report on impact assessment and trends in research pertaining to accumulation and curbing the menace of polyaromatic hydrocarbon (PAH) accumulation in leaves. Emphasis is given to understand the consequences of the fact that edible/medicinal plants cultivated in PAH contaminated soil or close to such places which are potential liberators of PAHs can virtually act as transporters for direct PAH entry into biological systems. An attempt has been made to predict the future by digging out golden facts from history.

Ultrathin tunable terahertz absorber based on MEMS-driven metamaterial.

The realization of high-performance tunable absorbers for terahertz frequencies is crucial for advancing applications such as single-pixel imaging and spectroscopy. Based on the strong position sensitivity of metamaterials' electromagnetic response, we combine meta-atoms that support strongly localized modes with suspended flat membranes that can be driven electrostatically. This design maximizes the tunability range for small mechanical displacements of the membranes.

[Preparation of drug containing extrusion pellets with a thermoplastic base. 2. The optimization of drug release].

The drug release can be improved by incorporation of additional auxiliary substances in extrusion pellets. The experimental results proved evidence, that especially the incorporation of calcium carbonate or polyvinylalcohol leads to an increase of the drug release. Their content must amount to 40%.

[Preparation of drugs in extrusion pellets with a thermoplastic base. 1. Drug liberation].

In connection with the preparation of solid sustained-release forms extrusion pellets were prepared. The conditions for the processing of the thermoplastics were determined. Lithium sulfate and caffeine served as model drugs.