Publications by authors named "H Kajiyama"

The growing recognition of the importance of interpregnancy weight management in reducing hypertensive disorders of pregnancy (HDP) underscores the importance of effective preventive strategies. However, developing effective systems remains a challenge. We aimed to bridge this gap by constructing a prediction model.

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  • The study aims to evaluate postpartum follow-up care for women with hypertensive disorders of pregnancy (HDP) in Japan, highlighting its importance for reducing future cardiovascular and metabolic disease risks.
  • A web-based survey conducted among postpartum women revealed low awareness of HDP-related risks, with only 56.2% knowing about cardiovascular disease risk and even fewer understanding metabolic syndrome risks or preventive measures.
  • The findings indicate that healthcare providers are not adequately informing patients, resulting in a lack of follow-up and awareness, emphasizing the need for better educational resources and follow-up protocols for women after pregnancy.
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  • Plasma-activated Ringer's lactate (PAL) is being explored as a cancer therapy with no known side effects, but it has been found to trigger autophagy, which may undermine its antitumor effects.
  • Research revealed that this autophagy can temporarily aid in the proliferation of MCF-7 human breast cancer cells upon exposure to PAL solution.
  • The study identified specific compounds in PAL, like acetate and 2,3-dimethyltartrate, that promote autophagy, and noted that 2,3-dimethyltartrate can either cause cell death or trigger autophagy depending on its concentration.
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Background: The accumulation of ascites is a major symptom of ovarian cancer. The volume of ascites is a pathophysiological indicator of the peritoneal environment, such as inflammation and fibrosis; however, the relationship between the volume of ascites and oncological outcomes remains unclear. We herein retrospectively examined the effects of the volume of ascites on the prognosis of epithelial ovarian cancer in a multi-institutional large cohort using the stratification of clinical characteristics and statistical adjustment methods.

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Aim: To provide information including the trend of gynecological malignancies in Japan, we hereby present the Annual Patient Report for 2021 and the Annual Treatment Report for 2016, on the outcomes of patients who started treatment in 2016.

Methods: The Japan Society of Obstetrics and Gynecology maintains an annual tumor registry, where information on gynecological malignancies from various participating institutions is gathered. The data of patients whose treatment with gynecologic malignancies was initiated in 2021 were analyzed retrospectively.

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