Publications by authors named "H Kajio"

There are no clear strategies for non-insulin-dependent slowly progressive type 1 diabetes mellitus (SPIDDM). We herein report a 25-year-old man with SPIDDM in whom appropriate diet therapy and exercise improved the initial insulin secretion without medication. After 12 months, his body weight decreased by 5.

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Insulin treatment should be introduced in patients with slowly progressive type 1 diabetes (SPIDDM; definite), according to the revised diagnostic criteria of SPIDDM (2023). In contrast, SPIDDM (probable) patients are in a non-insulin-dependent state; therefore, a more flexible treatment can be considered, although sulfonylurea agents should be avoided. Insulin treatment has been shown to maintain endogenous insulin secretion capacity in SPIDDM (probable); however, this does not mean that all SPIDDM (probable) patients should use insulin from the early phase.

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Background: The increasing incidence and prevalence of childhood overweight (OW) and obesity (OB) are major global health challenges. This study aimed to evaluate the effectiveness of a 2-year healthy lifestyle intervention program in reducing the incidence of OW and OB among schoolchildren aged 11-12 years in Vietnam.

Methods: Study design: Randomized controlled trial.

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Complete medical examinations are a system of preventive medicine unique to Japan. In recent years, Japanese and foreigners have been aware of complete medical examinations. However, the extent to which this concept of comprehensive medical checkup is recognized in different counties is unknown.

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Article Synopsis
  • The study investigates how age-related biomarkers can help predict health issues in older diabetes patients, focusing on those aged 60 and above.
  • Conducted with 115 Japanese patients, the research tracks health outcomes like hospitalization and nursing home admissions, linking them to specific biomarkers and clinical indicators.
  • Results indicate that higher levels of GDF15 and adiponectin, along with a clinical measure called the Barthel Index, are significantly associated with negative health outcomes, suggesting these could serve as useful predictive tools.
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