Given the diverse molecular pathways involved in tumorigenesis, identifying subgroups among cancer patients is crucial in precision medicine. While most targeted therapies rely on DNA mutation status in tumors, responses to such therapies vary due to the many molecular processes involved in propagating DNA changes to proteins (which constitute the usual drug targets). Though RNA expressions have been extensively used to categorize tumors, identifying clinically important subgroups remains challenging given the difficulty of discerning subgroups within all possible RNA-RNA networks.
View Article and Find Full Text PDFHosp Pharm
December 1992
The purpose of this study was to inventory the highly specialized units maintained in teaching hospitals and compare and contrast the scope and level of pharmaceutical services provided in teaching and similar-size community hospitals. In 1989, a 30-item questionnaire was mailed to a sample of 120 teaching hospitals. The scope and level of services provided was compared with similar size hospitals in the 1989 American Society of Hospital Pharmacists' survey of hospital-based pharmaceutical services.
View Article and Find Full Text PDFThe impact of dual systems of health care on those who use them is not well understood. A study was undertaken in Nigeria to study this impact. A questionnaire about use of dual health care systems was prepared and tested and then administered to a study sample.
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