Publications by authors named "H K van den Tooren-de Groot"
Some microbes in the rumen form 10,12 (10,12)-conjugated linoleic acid (CLA), a fatty acid that depresses synthesis of milk fat in dairy cattle and other lactating animals. Despite their importance to milk fat depression, the microbes responsible have been difficult to identify, and no laboratory strain is currently available for study. Here we describe the isolation of AP1, a bacterium that forms 10,12-CLA at fast rates.
View Article and Find Full Text PDFBackground: Assessment of health-related quality of life (HRQoL) in patients with cardiovascular disease (CVD) is impaired by limitations of current patient-reported outcome measures (PROMs). We developed the first cardiovascular disease (CVD) specific electronic PROM for which health items were derived by a fully patient-centered method. This paper reports on the measurement of HRQoL in CVD patients by a novel developed electronic patient-centred PROM based on a preference-based measurement model.
View Article and Find Full Text PDFObjective: Elderly patients with chronic limb-threatening ischemia (CLTI) undergoing revascularization are prone to delirium and prolonged hospitalization. Preoperative prehabilitation may prevent delirium and reduce the length of stay. This study investigates the effect of multimodal prehabilitation on delirium incidence in elderly patients with CLTI undergoing revascularization.
View Article and Find Full Text PDFArticle Synopsis
- Zebrafish serve as a key model for studying neurodegenerative diseases, but achieving cellular resolution in their brain imaging has been difficult.
- The study presents groundbreaking MRI results at a high magnetic field strength of 28.2 T, achieving a 20% better signal-to-noise ratio compared to the previous 17.6 T, allowing for clearer brain structure visualization.
- Advanced imaging techniques like diffusion tensor imaging (DTI) and constrained spherical deconvolution are used to non-invasively identify white matter structures with high resolution, paving the way for better understanding of microstructural changes in zebrafish models of brain diseases.
Article Synopsis
- A study evaluated a personalized eHealth app designed for abdominal aortic aneurysm (AAA) patients undergoing surgery to assess patient satisfaction and feasibility.
- Out of 65 patients, 91% installed the app, with high satisfaction scores for guidance, information, and overall usefulness, although 10% deactivated it.
- The app is considered a valuable tool for enhancing prehabilitation and contributes to the digital transformation in healthcare, with users reporting positive lifestyle changes and areas for improvement.