Publications by authors named "H K Sokhi"
Background And Objective: Magnetic resonance imaging (MRI) can detect recurrences after focal therapy for prostate cancer but there is no robust guidance regarding its use. Our objective was to produce consensus recommendations on MRI acquisition, interpretation, and reporting after focal therapy.
Methods: A systematic review was performed in July 2022 to develop consensus statements.
Article Synopsis
- The study aimed to compare biopsy recommendation rates and accuracy between the Prostate Imaging-Reporting and Data System version 2 (PI-RADSv2) and the Likert scale for detecting significant and insignificant prostate cancer in men aged 50-69 participating in the IP1-PROSTAGRAM trial.
- Men were screened using Prostagram MRI, and results showed that more patients were recommended for biopsy with the Likert scale compared to PI-RADSv2 when the MRI score was ≥3, though accuracy in detecting cancer was similar for both systems.
- The findings indicate that while the Likert scale may suggest more biopsy recommendations, both methods have comparable effectiveness in identifying clinically significant prostate cancer.
Objectives: Whole-body magnetic resonance imaging (WB-MRI) has been demonstrated to be efficient and cost-effective for cancer staging. The study aim was to develop a machine learning (ML) algorithm to improve radiologists' sensitivity and specificity for metastasis detection and reduce reading times.
Materials And Methods: A retrospective analysis of 438 prospectively collected WB-MRI scans from multicenter Streamline studies (February 2013-September 2016) was undertaken.
Background: The use of prostate-specific antigen (PSA) testing to screen for prostate cancer has been fraught with under- and overdiagnosis. Short, noncontrast magnetic resonance imaging (MRI) might detect more grade group ≥2 cancers with similar rates of biopsy.
Objective: To evaluate strategies that combined PSA and MRI to select men based in the community for a prostate biopsy.
Background: The IP1-PROSTAGRAM study showed that a short, non-contrast MRI detected more significant cancers with similar rates of biopsy compared to PSA. Herein, we compare the expected and perceived burden of PSA, MRI and ultrasound as screening tests.
Methods: IP1-PROSTAGRAM was a prospective, population-based, paired screening study of 408 men conducted at seven UK primary care practices and two imaging centres.