Comparative pharmacokinetics and bioavailability of flavonoid glycosides of Ginkgo biloba after a single oral administration of three formulations to healthy volunteers.

Eighteen healthy volunteers received three different formulations of Ginkgo biloba: capsules (A) and drops (B) (delivered by Agon Pharma), and tablets (C) (Tebonin-Dr. W. Schwabe) in equal an quantity, orally as a single dose, at an interval of at least five days.

[Treatment of chronic ischemia of the lower extremities with complex herbal preparation].

Chronic ischemia of the lower extremities with atherosclerosis background is being manifested by intermittent claudication. For treating the intermittent claudication many drugs are used, which may give rise to therapeutical side effects. In 50 patients with diagnosed arteriosclerosis affecting the lower extremities in II stage according to Fontain, a vegetable preparation PADMA-28 was applied for 16 weeks.

[Acute intermittent porphyria--diagnostic difficulties and treatment].

A patient is described in whom acute intermittent porphyria was diagnosed after 6 months of treatment and five stays in hospital during which the cause of her manifestations was not established. Treatment of the patient and principles of treatment of acute attack of intermittent porphyria are described.

[Evaluation of the circulatory system in workers exposed to caprolactam and diphenyl in 1 of the chemical plants producing polyamine fibers].

The literature data indicating nonspecific pathologic symptoms of the circulatory system in those occupationally exposed to caprolactam and diphenyl inspired the authors to evaluate the circulatory system in a group of 495 workers of a Chemical Plant producing polyamide fibres. The anamnestic data, family inquiry and subjective changes indicate that any hints of the significant effects of the technological process on circulatory diseases in this professional group are unwarranted. The percentage values of the latent circulatory failure (1-2% of subjects), coronary insufficiency (6.