Acute propafenone toxicity after two exposures at standard dosing.

A 72-year-old woman presented with a decreased level of consciousness and hypotension. The initial electrocardiogram demonstrated atrial fibrillation with a wide QRS complex. Her medical history revealed that she had just been started on propafenone.

Adverse reproductive and child health outcomes among people living near highly toxic waste water drains in Punjab, India.

Background: Environmental influence plays a major role in determining health status of individuals. Punjab has been reported as having a high degree of water pollution due to heavy metals from untreated industrial effluent discharge and high pesticide consumption in agriculture. The present study ascertained the association of heavy metal and pesticide exposure on reproductive and child health outcomes in Punjab, India.

Identifying missed opportunities to curtail antimicrobial therapy for presumed ventilator-associated pneumonia using the clinical pulmonary infection score.

Background: Early discontinuation of antimicrobial therapy for ventilator-associated pneumonia can reduce the emergence of antimicrobial resistance, the occurrence of adverse drug events, and the cost of therapy. Evidence suggests that discontinuation of therapy by day 3 may be appropriate for patients with a clinical pulmonary infection score of 6 or less at baseline and on day 3.

Objectives: To determine the proportion of patients eligible for antimicrobial discontinuation on day 3 and day 7 of therapy and to determine the proportion of eligible patients for whom antimicrobials were discontinued within these timeframes.

Epidemiological study of high cancer among rural agricultural community of Punjab in Northern India.

Based on a citizen's report, a house-to-house survey was conducted in Talwandi Sabo and Chamkaur Sahib Community Development Blocks in Bathinda and Roop Nagar District respectively in Punjab state located in a northern part of India to identify the number of existing cancer cases, and the number of cancer deaths that occurred in the last 10 years. Age adjusted prevalence of confirmed cancer cases per 100,000 population was 125 (107/85315) in Talwandi Sabo and 72 (71/97928) in Chamkaur Sahib. Cancer of female reproductive system, i.

Association of outdoor air pollution with chronic respiratory morbidity in an industrial town in northern India.

A cross-sectional study was performed in one industrial (study) and one non-industrial (reference) town in Punjab State, northern India. Ambient air quality samples were collected and analyzed each week for 2 yr. Subjects were 3,603 individuals >15 yr old who were interviewed and whose lung functions were measured spirometrically.