Publications by authors named "H K Mahmood"
The G20 countries are responsible for around 75% of the world's greenhouse gas (GHG) emissions, including the use of natural resources. In this regard, the role of globalization in achieving environmental sustainability is a relatively new topic of concern. As a result, the present study considers how globalization and natural resources affect GHG emissions, as well as the roles that renewable energy consumption and urbanization play in the G20 countries between 1990 and 2020.
View Article and Find Full Text PDFArticle Synopsis
- Oral epithelial dysplasia (OED) is challenging due to its risk of turning malignant and the unreliability of current grading systems to predict this, leading to high observer variability.
- A new AI-based score focusing on intra-epithelial lymphocytes (IELs) was developed to assess OED using a digital dataset of 219 tissue samples, which outperformed traditional pathologist evaluations.
- The study found that higher IEL scores were significantly linked to more severe OED and a greater likelihood of malignant transformation, suggesting IELs could serve as valuable prognostic indicators.
Background: Exacerbations of asthma and chronic obstructive pulmonary disease (COPD) are important events and are associated with critical illness. Eosinophilic inflammation is a treatable trait commonly found during acute exacerbations of asthma and COPD. We hypothesised that for patients with eosinophilic exacerbations, a single injection of benralizumab, a humanised monoclonal antibody against interleukin-5 receptor-α, alone or in combination with prednisolone, will improve clinical outcomes compared with prednisolone, the standard of care.
View Article and Find Full Text PDFBackground: Despite extensive research over the decades, cancer therapy is still a great challenge because of the non-specific delivery of chemotherapeutic agents, which could be overcome by limiting the distribution of chemotherapeutic agents toward cancer cells.
Objective: To reduce the cytolytic effects against cancer cells, graphene oxide (GO) nanoparticles (NPs) can load anticancer medicines and genetic tools.
Methodology: During the current study, folic-acid-conjugated graphene oxide (Fa-GO) hybrid mucoadhesive chitosan (CS)-based hydrogel beads were fabricated through an "ion-gelation process", which allows for regulated medication release at malignant pH.