Designing a replacement heifer rearing strategy: Effects of growth profile on performance of Norwegian Red heifers and cows.

The primary objective of this study was to design a growth profile from 3 mo through puberty to insemination that allows heifers to enter the milking herd at 22 mo of age without impairing milk production over 3 lactations compared with the current rearing practice leading to an age at first calving of 26 mo. Eighty heifers born into the Norwegian University of Life Sciences herd, 40 each from yr 2010 and 2011, were randomly assigned according to birth order either to a high or low intake energy treatment. Each energy group was further subdivided into 2 protein groups, 1 fed according to requirements and 1 fed 10% excess protein, to ensure that metabolizable protein supply would meet the requirements for rapidly growing bone and muscle of today's genetically improved Norwegian Red heifer.

Long-term effects of prior diets, dietary transition and pregnancy on adipose gene expression in dairy heifers.

Adipose tissue is highly involved in whole-body metabolism and is the main site for lipid synthesis, storage and mobilization in ruminants. Therefore, knowledge about adipose tissue responses to different diets is important, especially in growing heifers as the feeding regimes of replacement heifers affect their future success as dairy cows. However, at gene expression level such knowledge is limited.

RNA-seq analysis of bovine adipose tissue in heifers fed diets differing in energy and protein content.

Adipose tissue is no longer considered a mere energy reserve, but a metabolically and hormonally active organ strongly associated with the regulation of whole-body metabolism. Knowledge of adipose metabolic regulatory function is of great importance in cattle management, as it affects the efficiency and manner with which an animal converts feedstuff to milk, meat and fat. However, the molecular mechanisms regulating metabolism in bovine adipose tissue are still not fully elucidated.