Social media activism and women's health: Endometriosis awareness and support.

Objective: While endometriosis is estimated to affect 1 in 10 women globally, awareness of the disease as well as research and funding to fight the disease remains lacking as compared with other chronic diseases. This study examines how social media users utilized Instagram to raise awareness of and mobilize activism around endometriosis by analyzing prominent topics, word associations, and feminism themes in endometriosis-tagged posts on Instagram.

Methods: We used a mixed-method approach of combining computational analyses (topic modeling and word association) and human coding (qualitative thematic analysis) of Instagram posts on endometriosis.

Profile of snakebite cases admitted to the Poison Control Center of Bach Mai Hospital in northern Vietnam from 2008 to 2020.

Background: Vietnam harbours a high species richness of venomous snakes with >60 recognised species but snakebite pathology and treatment are still understudied, particularly in northern Vietnam.

Methods: A retrospective study from 2008 to 2020 was conducted, focusing on snakebite cases at the Poison Control Center of Bach Mai Hospital, a major centre in northern Vietnam for treating envenoming incidents.

Results: A total of 5805 snakebite cases were reported over 12 y.

Molecular basis of Spns1-mediated lysophospholipid transport from the lysosome.

Spns1 mediates the rate-limiting efflux of lysophospholipids from the lysosome to the cytosol. Deficiency of Spns1 is associated with embryonic senescence, as well as liver and skeletal muscle atrophy in animal models. However, the mechanisms by which Spns1 transports lysophospholipid and proton sensing remain unclear.

Ionic Diode-Based Drug Delivery System.

Drug delivery systems hold promise for delivering cytotoxic drugs by controlling the timing and location of the drug release. However, conventional delivery mechanisms often fall short of achieving spatiotemporally controlled yet sustained release, which is crucial for ensuring drug efficacy and minimizing impact on surrounding tissues. Here, an ionic diode-based drug delivery system is reported that is controlled by an electric potential and capable of releasing drugs at scales ranging from nanogram to microgram.