Publications by authors named "H K Alakhras"
Article Synopsis
- The study evaluated the surface roughness and color stability of various resin composites, including new ones with color adjustment capability, after immersion in staining solutions like cola, coffee, and black tea.
- Filtek Z350XT showed the lowest surface roughness, significantly different from other composites with color adjustment potential, which had similar roughness levels.
- In terms of color change, Neo Spectra ST had the least color change, while Omnichroma and Charisma Diamond One exhibited the most significant color changes after exposure to staining solutions.
Article Synopsis
- * A 79-year-old man experienced severe heart block after undergoing procedures for a urinary issue, prompting a thorough examination that ruled out common heart problem causes.
- * Advanced imaging revealed cardiac sarcoidosis despite the absence of lung involvement, leading to a diagnosis and subsequent treatment, which included the installation of a defibrillator and oral corticosteroids.
While cardiac tamponade is a commonly recognized complication in solid organ malignancies and acute leukemias, instances of cardiac involvement in the context of chronic hematologic malignancies, such as chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), are rarely observed. A 66-year-old male, with a history of stage IV CLL/SLL, presented with three weeks of worsening edema, orthopnea, and dyspnea. Two days after admission, an echocardiogram revealed a large circumferential pericardial effusion.
View Article and Find Full Text PDFSafety and efficacy of Rucaparib in the treatment of ovarian cancer and patients with BRCA mutation: a systematic review and meta-analysis of phase III randomized clinical trials.
Expert Rev Anticancer Ther
February 2024
Introduction: Our systematic review and meta-analysis aimed to evaluate the clinical efficacy and safety of Rucaparib, a PARP inhibitor (PARPi), in patients with ovarian cancer and BRCA mutation.
Methods: Online databases were comprehensively searched for all phase III Randomized trials that used Rucaparib therapy for ovarian cancer patients and patients having BRCA mutation. Efficacy results are progression-free survival and overall response rate in addition to addressing its safety concerns.
Unilateral adrenal hemorrhage is a rare but deadly complication that can occur secondary to causes such as trauma and metastasis. A 55-year-old male with a history of metastatic lung adenocarcinoma and deep vein thrombosis managed with rivaroxaban presented with acute right abdominal and flank pain. A CT angiogram of the abdomen showed a retroperitoneal hematoma around the right adrenal gland, consistent with a unilateral adrenal hemorrhage.
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