Detection and Isolation of Camelpox Virus in Wasit Province, Iraq.

Camels are susceptible to a variety of infectious diseases, such as trypanosomiasis, anthrax, hemorrhagic septicemia, brucellosis, mange, and pox, which can also affect other farm animal species. Camelpox is one of the most infectious skin diseases, which is caused by the Camelpox virus (CPV), a member of the Orthopoxvirus genus in the Poxviridae family. This study mainly aimed to detect and isolate CPV affecting camels in Wasit province, Iraq.

Assessment of Contagious Ecthyma Virus in Camels of Wasit Province, Iraq.

Camel contagious ecthyma (CCE) is an infectious disease caused by the Paravox virus (PPV) of the family . Due to the importance of the camel breeding industry in tropical and subtropical regions, the present study aimed to isolate the causative agent of camel contagious ecthyma (CCE) using cell culture and molecular confirmation of virus isolate. A total of 210 camels aged 6 months to 4 years were selected from different districts in Wasit province (Iraq) from August 2017 to April 2019.

Cadherin-related protein 24 induces morphological changes and partial cell polarization by facilitating direct cell-cell interactions.

Cadherin-related protein 24 (CDHR24) is a potential tumor suppressor located apically as well as laterally in polarized cells. Here, the role of CDHR24 in contributing to cell morphology and polarity is examined. CDHR24 was predominantly localized at the nonattached part of nonpolarizing cells while another apically sorted protein, aminopeptidase N, was equally distributed over the plasma membrane.

Binding of anti-GRP78 autoantibodies to cell surface GRP78 increases tissue factor procoagulant activity via the release of calcium from endoplasmic reticulum stores.

The increased risk of venous thromboembolism in cancer patients has been attributed to enhanced tissue factor (TF) procoagulant activity (PCA) on the surface of cancer cells. Recent studies have shown that TF PCA can be modulated by GRP78, an endoplasmic reticulum (ER)-resident molecular chaperone. In this study, we investigated the role of cell surface GRP78 in modulating TF PCA in several human cancer cell lines.