Publications by authors named "H Jonathan Groot"
Objective: Elderly patients with chronic limb-threatening ischemia (CLTI) undergoing revascularization are prone to delirium and prolonged hospitalization. Preoperative prehabilitation may prevent delirium and reduce the length of stay. This study investigates the effect of multimodal prehabilitation on delirium incidence in elderly patients with CLTI undergoing revascularization.
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- Zebrafish serve as a key model for studying neurodegenerative diseases, but achieving cellular resolution in their brain imaging has been difficult.
- The study presents groundbreaking MRI results at a high magnetic field strength of 28.2 T, achieving a 20% better signal-to-noise ratio compared to the previous 17.6 T, allowing for clearer brain structure visualization.
- Advanced imaging techniques like diffusion tensor imaging (DTI) and constrained spherical deconvolution are used to non-invasively identify white matter structures with high resolution, paving the way for better understanding of microstructural changes in zebrafish models of brain diseases.
Article Synopsis
- A study evaluated a personalized eHealth app designed for abdominal aortic aneurysm (AAA) patients undergoing surgery to assess patient satisfaction and feasibility.
- Out of 65 patients, 91% installed the app, with high satisfaction scores for guidance, information, and overall usefulness, although 10% deactivated it.
- The app is considered a valuable tool for enhancing prehabilitation and contributes to the digital transformation in healthcare, with users reporting positive lifestyle changes and areas for improvement.
Successful Introduction of Peanut in Sensitized Infants With Reported Reactions at Home.
J Allergy Clin Immunol Pract
December 2024
Article Synopsis
- Early introduction of peanut for high-risk infants may help prevent peanut allergies, but it's unclear how to best diagnose reactions reported at home.
- In a study of 186 infants who had reactions to peanut, 69% showed sensitization, but 73% of the oral food challenges were negative, allowing safe home introduction of peanut.
- After 6 months, 96% of infants continued consuming peanut regularly without reactions, indicating that testing can prevent misdiagnosis and support long-term tolerance.*
Galectin-3 and Suppression of tumorigenicity-2 (ST2) are known markers of cardiac fibrosis. We investigated the prognostic value of fibrotic markers for the development of diastolic dysfunction and long-term outcome in patients suffering an ST-elevated myocardial infarction (STEMI). We analyzed 236 patients from the GIPS-III cohort with available echocardiographic studies and plasma measurements at hospitalization and after 4 months follow-up.
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