Publications by authors named "H Johansen"
Article Synopsis
- The text discusses the development of a serological test to identify a sexually transmitted pathogen that affects reproductive health in both genders.
- It highlights the challenges faced due to cross-reactivity with a similar respiratory pathogen, making accurate testing difficult.
- The newly developed immunoblot assay shows promising results with a sensitivity of 87.1% and specificity of 95.2%, which could enhance understanding of the pathogen's impact on reproductive complications.
Primary ciliary dyskinesia is a rare genetic disorder characterized by progressive lung disease. is a major pathogen in this disease, known to impact lung function. Previous genotype-phenotype studies have been limited by cross-sectional designs, isolated adult or pediatric populations, small numbers, or short follow-up durations.
View Article and Find Full Text PDFMacrolides are widely used antibiotics for the treatment of bacterial airway infections. Due to its elevated minimum inhibitory concentration in standardized culture media, Pseudomonas aeruginosa is considered intrinsically resistant and, therefore, antibiotic susceptibility testing against macrolides is not performed. Nevertheless, due to macrolides' immunomodulatory effect and suppression of virulence factors, they are used for the treatment of persistent P.
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- * A study replicated this by testing participants with both phonemic and semantic word evaluation tasks and found that while semantic processing led to better recognition, it did not confirm the advantage of MH over cRH.
- * The results indicated no significant difference between the MH and cRH groups in their ability to learn verbally incidental material, challenging previous research findings and suggesting the need for further investigation into the reasons behind these discrepancies.
Transforming growth factor-beta 1 (TGF-β1) is a critical regulator of skeletal homeostasis and has diverse effects on osteoblastogenesis. To date, the mechanisms behind the intriguing inhibitory effect of TGF-β1 on osteoblast maturation are not fully understood. Here, we demonstrate a novel mechanism by which TGF-β1 modulates osteoblast maturation through the lysosomal protease legumain.
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