Type 2 diabetes mellitus (T2DM) is a global health challenge with limited efficacy of current treatments, necessitating alternative therapies. Plant-derived pectin, composed of galacturonic acid and structural domains such as homogalacturonan, has shown promise as an anti-diabetic agent. Pectin exerts its therapeutic effects through multiple mechanisms, including enhancing β-cell function, regulating glucose metabolism, improving insulin sensitivity, inhibiting digestive enzymes, and restoring gut microbiota balance.
View Article and Find Full Text PDFBackground: Western dietary patterns are well-established risk factors for coronary heart disease (CHD); however, the potential role of Traditional Chinese Medicine (TCM) dietary theory in exacerbating specific TCM syndromes among CHD patients remains a significant knowledge gap. To address this gap, our study aimed to investigate the relationship between dietary patterns, encompassing diet tastes and eating habits, and the occurrence of Heart-Related Blood Vessel Syndromes (HRBVS) in Chinese patients with CHD.
Methods: Data from 4428 patients with CHD were collected, including 2,973 stable angina pectoris (SAP) cases, 614 acute coronary syndrome (ACS) cases, and 841 heart failure (HF) cases.
Background: An increasing number of studies to date have found preoperative magnetic resonance imaging (MRI) features valuable in predicting the prognosis of rectal cancer (RC). However, research is still lacking on the correlation between preoperative MRI features and the risk of recurrence after radical resection of RC, urgently necessitating further in-depth exploration.
Aim: To investigate the correlation between preoperative MRI parameters and the risk of recurrence after radical resection of RC to provide an effective tool for predicting postoperative recurrence.
World J Gastroenterol
March 2025
Non-alcoholic fatty liver disease (NAFLD) has emerged as a global public health concern, affecting over one-quarter of the global population. It is closely associated with the prevalence of obesity and metabolic syndrome. Current treatment options for NAFLD are limited and often have side effects.
View Article and Find Full Text PDFBackground: Hepatitis E virus (HEV) infection during pregnancy is associated with obstetric complications and adverse maternal and neonatal outcomes. This study aimed to determine the seroprevalence of HEV and RNA positivity in both healthy pregnant women and women coinfected with hepatitis B virus (HBV).
Methods: A cross-sectional study was conducted involving 528 pregnant women (278 with and 250 without hepatitis B surface antigen [HBsAg]) in their third trimester.